Name: Easy Cheesy Cajun Garlic Chicken Rotini Skillet Dinner
Prep time: 15 min
Cook time: 30 min
Total time: 45 min
Yield: 4 servings
Ingredients: 1 pound Chicken Breasts; 8 ounces Rotini Pasta; 2 tablespoons Olive Oil; 1 tablespoon Cajun Seasoning; 1 teaspoon Garlic Powder; 1 teaspoon Onion Powder; to taste Salt; to taste Pepper; 2 cloves Garlic, minced; 2 tablespoons Butter; 1 cup Heavy Cream; 1 cup Chicken Broth; 1 cup Mozzarella Cheese; ½ cup Parmesan Cheese; ½ cup Cheddar Cheese

Cheesy Cajun Garlic Chicken Rotini Skillet – get ready to transform your weeknight dinner routine with a dish that promises an explosion of flavor! I absolutely adore how this recipe brings the vibrant spirit of Louisiana right into my kitchen, offering a delightful blend of rich, bold Cajun spices with comforting Italian-inspired pasta. While not steeped in ancient traditions, this modern skillet creation beautifully marries the zesty, aromatic essence of Cajun cooking – a cuisine born from French, Spanish, and African influences in the bayous – with universally loved ingredients like tender chicken, perfectly cooked rotini, and a generous blanket of cheese.

Why This Skillet Meal Will Become Your New Favorite!

People simply can’t get enough of this dish, and it’s easy to see why. The irresistible combination of succulent chicken, infused with robust garlic and fiery Cajun seasoning, all tossed with spiral pasta in a creamy, cheesy sauce, delivers an unparalleled sensory experience. It’s the ultimate comfort food that doesn’t compromise on taste or convenience. Preparing this Cheesy Cajun Garlic Chicken Rotini Skillet is not only incredibly straightforward, making it perfect for busy evenings, but it also offers a fantastic balance of creamy texture and a delightful kick that will have everyone reaching for seconds. Trust me, it’s a culinary journey you’ll want to take again and again!

Ingredients:

For the Chicken:
- 2 large (about 1.5 lbs) boneless, skinless chicken breasts, cut into 1-inch cubes
- 2 tablespoons olive oil, plus extra if needed
- 1 tablespoon Cajun seasoning blend (store-bought or your favorite homemade mix)
- ½ teaspoon salt, or to taste
- ¼ teaspoon black pepper, or to taste
For the Pasta:
- 12 ounces (about 340g) rotini pasta (or your favorite short pasta like penne or fusilli)
- Water for boiling pasta
- 1 tablespoon salt for pasta water
For the Skillet Sauce and Veggies:
- 2 tablespoons unsalted butter
- 1 large yellow onion, finely chopped
- 1 medium green bell pepper, cored, seeded, and diced
- 1 medium red bell pepper, cored, seeded, and diced
- 4-6 cloves garlic, minced (I love garlic, so I tend to go for 6!)
- 1 tablespoon all-purpose flour (this helps thicken our sauce nicely)
- 2 cups low-sodium chicken broth
- 1 cup heavy cream
- 4 ounces (½ block) cream cheese, softened and cut into cubes
- 1 tablespoon Worcestershire sauce (optional, but it adds a wonderful depth of flavor!)
- 1 teaspoon Cajun seasoning blend (adjust to your spice preference)
- ½ teaspoon dried oregano
- Salt and freshly ground black pepper to taste
For the Cheesy Finish:
- 2 cups shredded sharp cheddar cheese
- 1 cup shredded Monterey Jack cheese (or use a pre-shredded Colby Jack blend for convenience)
For Garnish (Optional):
- ¼ cup fresh parsley, chopped
- A pinch of red pepper flakes for extra heat

Preparing Our Cheesy Cajun Garlic Chicken Rotini Skillet: The Chicken

Let’s kick things off by getting our chicken prepped and beautifully browned. This first step is crucial for building a fantastic flavor base for our entire Cheesy Cajun Garlic Chicken Rotini Skillet.

First things first, grab your boneless, skinless chicken breasts. I like to cut mine into nice, even 1-inch cubes. This ensures they cook quickly and evenly, and you get a good piece of chicken in every bite of our delicious skillet.
In a medium bowl, toss those chicken cubes with 1 tablespoon of Cajun seasoning, ½ teaspoon of salt, and ¼ teaspoon of black pepper. Make sure every piece is nicely coated – those seasonings are going to bring so much life to the chicken!
Now, heat your large, heavy-bottomed skillet (a 12-inch skillet works perfectly for this recipe) over medium-high heat. Add 2 tablespoons of olive oil. You want the oil to shimmer, but not smoke, before adding the chicken.
Once the oil is hot, carefully add the seasoned chicken to the skillet. Make sure not to overcrowd the pan; if necessary, cook the chicken in two batches. Overcrowding will steam the chicken instead of searing it, and we want a lovely golden-brown crust!
Cook the chicken for about 4-6 minutes, stirring occasionally, until it’s beautifully browned on all sides and cooked through. It should no longer be pink in the center. Once done, remove the cooked chicken from the skillet and set it aside on a plate. Don’t worry about any browned bits left in the pan – those are pure flavor that we’ll incorporate into our sauce!

Building the Flavor Foundation: Veggies and Aromatics

With the chicken cooked and set aside, it’s time to build the heart of our Cheesy Cajun Garlic Chicken Rotini Skillet: the aromatic vegetable base and the rich, creamy Cajun sauce. This is where all the magic truly starts to happen!

Reduce the heat in your skillet to medium. Add 2 tablespoons of unsalted butter to the same skillet where you cooked the chicken. Let it melt and sizzle gently, scraping up any delicious browned bits (fond) from the bottom of the pan as it melts. These bits are packed with flavor!
Add the finely chopped yellow onion, diced green bell pepper, and diced red bell pepper to the skillet. Sauté them for about 5-7 minutes, stirring frequently, until they become tender and slightly softened. You’ll notice a wonderful aroma filling your kitchen – that’s a sign you’re on the right track!
Now, it’s time for the superstar aromatic: garlic! Add the minced garlic to the skillet and cook for just 1 minute more, stirring constantly. Be careful not to let the garlic burn, as burnt garlic can taste bitter. We’re looking for fragrant, not toasted.
Next, sprinkle 1 tablespoon of all-purpose flour over the sautéed vegetables. Stir it well for about 1-2 minutes, allowing the flour to cook out a bit. This step is crucial; the flour acts as a roux, helping to thicken our sauce later and ensuring it’s wonderfully creamy, not watery.

Crafting the Creamy Cajun Sauce for Our Cheesy Cajun Garlic Chicken Rotini Skillet

Now that our aromatics are fragrant and our flour is cooked, it’s time to transform this skillet into the incredibly rich and flavorful sauce that will envelop our chicken and rotini. This creamy Cajun sauce is what makes this Cheesy Cajun Garlic Chicken Rotini Skillet so irresistible!

Pour in 2 cups of low-sodium chicken broth, stirring constantly to whisk away any lumps created by the flour. As you stir, you’ll notice the sauce starting to thicken beautifully. Bring it to a gentle simmer, allowing it to bubble for a couple of minutes until it’s slightly reduced.
Next, stir in 1 cup of heavy cream. This is where our sauce really starts to get that luxurious, velvety texture. Continue to stir gently as the cream warms through and integrates with the broth.
Add the cubes of softened cream cheese to the simmering sauce. Stir continuously until the cream cheese is fully melted and smoothly incorporated into the sauce. This adds an incredible tang and extra richness that sets our sauce apart.
Now, let’s dial up that Cajun flavor! Stir in the additional 1 teaspoon of Cajun seasoning blend and ½ teaspoon of dried oregano. If you’re feeling adventurous or love a bit more spice, feel free to add a little extra Cajun seasoning here. This is also the perfect moment to add 1 tablespoon of Worcestershire sauce, if you’re using it. It truly adds a layer of savory depth that you won’t regret!
Taste the sauce and adjust seasonings as needed. Add salt and freshly ground black pepper to your preference. Remember that the cheese we add later will contribute some saltiness, so be mindful not to over-salt at this stage. You want a sauce that’s vibrant and balanced.

Integrating the Pasta and Assembling Our Cheesy Cajun Garlic Chicken Rotini Skillet

We’re on the home stretch now! With our amazing Cajun cream sauce simmering, it’s time to bring in the starches and our glorious chicken, making this a truly complete and comforting Cheesy Cajun Garlic Chicken Rotini Skillet. The timing here is key to ensure everything comes together perfectly.

While you are preparing the sauce, bring a large pot of heavily salted water to a rolling boil. Add your 12 ounces of rotini pasta and cook according to package directions until al dente. It’s crucial to cook the pasta just until al dente, meaning it’s still firm to the bite, as it will continue to cook slightly when added to our hot skillet sauce.
Before draining the pasta, reserve about ½ cup of the starchy pasta water. This liquid is a secret weapon; it can be used to thin out the sauce if it becomes too thick, and the starch helps the sauce cling better to the pasta.
Drain the pasta thoroughly. Immediately add the cooked and drained rotini pasta directly into the skillet with your simmering Cajun cream sauce. Toss everything together gently until the pasta is completely coated in the luscious sauce.
Return the cooked chicken cubes to the skillet with the pasta and sauce. Stir everything together one last time, making sure the chicken is well distributed throughout the pasta and coated in the savory sauce. Allow it to heat through for about 1-2 minutes.

The Grand Finale: Cheesy Goodness and Serving Our Skillet

This is the moment we’ve all been waiting for – the ultimate cheesy finish! Adding the cheeses will transform our delicious chicken and pasta into a truly indulgent and comforting Cheesy Cajun Garlic Chicken Rotini Skillet that everyone will adore. Get ready for some serious stretch and ooey-gooey goodness!

Remove the skillet from the heat. This is important because we want the cheese to melt into the sauce, not seize up or get oily from too much direct heat.
Sprinkle in the 2 cups of shredded sharp cheddar cheese and 1 cup of shredded Monterey Jack cheese evenly over the pasta and chicken.
Gently stir the cheeses into the hot pasta mixture. Stir continuously until all the cheese has completely melted, creating a wonderfully creamy, stretchy, and incredibly cheesy sauce that coats every single piece of rotini and chicken. If the sauce seems a little too thick, you can add a splash or two of that reserved pasta water to reach your desired consistency.
Once the cheese is fully melted and incorporated, your Cheesy Cajun Garlic Chicken Rotini Skillet is ready to be devoured!
Serve immediately while it’s warm and gooey. Garnish with fresh chopped parsley for a touch of freshness and color, and a sprinkle of red pepper flakes if you’d like a little extra kick. This dish is fantastic on its own, but a simple green salad or some crusty bread for soaking up every last bit of that amazing sauce would make it a complete meal. Enjoy every cheesy, flavorful bite!

So, here we are at the end of our culinary journey, and I genuinely hope you’re feeling as excited as I am about this incredible recipe. This isn’t just another dish to add to your rotation; it’s truly a celebration of flavor, convenience, and pure comfort. If you’ve been searching for that perfect weeknight hero or an impressive meal to share with loved ones without spending hours in the kitchen, then look no further.

A Symphony of Flavors: Why This Recipe is a Must-Try

What makes this particular recipe so undeniably special? It’s the harmonious blend of robust, smoky Cajun spices with the luscious creaminess of melted cheese, all perfectly coating tender pieces of chicken and al dente rotini pasta. Then, add in the pungent warmth of garlic, which elevates every single bite, ensuring a truly unforgettable experience. Imagine sinking your fork into a swirl of pasta, embracing succulent chicken, all bathed in a rich, velvety sauce that offers a gentle kick, followed by a comforting, cheesy finish. It’s a dish that manages to be both deeply satisfying and surprisingly straightforward to prepare. The Cheesy Cajun Garlic Chicken Rotini Skillet is more than just a meal; it’s a moment of culinary bliss, designed to bring warmth and joy to your table with minimal fuss. It promises a dining experience that feels both indulgent and homey, striking that perfect balance between gourmet taste and everyday ease. For busy families, for dinner parties, or for a cozy night in, it consistently delivers on taste and simplicity, making it an absolute must-try for anyone who appreciates genuinely good food.

Make It Your Own! Serving Suggestions and Creative Variations

One of the many things I adore about this recipe is its incredible versatility. While it’s absolutely perfect as a stand-alone meal, there are countless ways to customize it and make it uniquely yours, catering to different tastes and dietary preferences. For a complete meal, I love serving this skillet dish alongside a crisp, refreshing side salad. A simple mixed green salad with a tangy vinaigrette offers a wonderful contrast to the richness of the pasta. Another fantastic accompaniment is a generous basket of crusty garlic bread or warm French baguette, perfect for soaking up every last drop of that delectable, cheesy sauce.

But don’t stop there! This recipe is a blank canvas for your culinary creativity:

Veggie Boost: Feel free to toss in some extra vegetables. Sautéed bell peppers (red, green, and yellow for a burst of color!), sliced mushrooms, or even a handful of fresh spinach (stirred in at the very end until wilted) would be fantastic additions. Corn kernels or diced tomatoes also blend beautifully with the Cajun flavors.
Protein Swap: While chicken is classic, don’t hesitate to experiment! Juicy shrimp would be an incredible addition, especially if added in the last few minutes of cooking to prevent overcooking. Sliced smoked sausage, particularly Andouille sausage, would amplify the Cajun authenticity and add another layer of smoky flavor. For a vegetarian twist, consider using hearty cannellini beans or chickpeas instead of meat.
Spice Level: If you’re a heat-seeker like me, feel free to amp up the spice! A pinch more cayenne pepper, a dash of your favorite hot sauce, or even a few finely diced jalapeños can take the heat up a notch. Conversely, if you prefer a milder flavor, simply reduce the amount of Cajun seasoning or choose a brand that’s less spicy.
Cheesy Choices: While cheddar and Monterey Jack are a fantastic combination, why not try other cheeses? Pepper Jack will give it an extra spicy kick, smoked Gouda will add depth, or a blend of Italian cheeses could offer a different character. A final sprinkle of freshly grated Parmesan cheese before serving is always a good idea too!
Pasta Alternatives: If rotini isn’t your preferred pasta shape, feel free to substitute with other short pasta varieties like penne, ziti, or cavatappi. For those with gluten sensitivities, a gluten-free pasta can be easily swapped in without compromising on flavor or texture.
Extra Creaminess: For an even richer, more decadent sauce, a splash of heavy cream or half-and-half can be stirred in at the end. Or, for a slightly lighter touch, you can always adjust the amount of chicken broth.
Fresh Herbs: A sprinkle of fresh parsley or cilantro just before serving adds a wonderful pop of color and a fresh, herbaceous note that brightens the entire dish.

Your Turn! Dive In and Share Your Culinary Journey!

Now that you have all the tips, tricks, and inspiration, it’s your turn to bring this magic to life in your own kitchen! I genuinely encourage you to roll up your sleeves, gather your ingredients, and give this recipe a try. I promise you won’t be disappointed. There’s something truly gratifying about creating a delicious, comforting meal from scratch, especially one that comes together with such ease and delivers on flavor every single time. Don’t just dream about it; make it!

And when you do, please, please, please come back and share your experience with me! I absolutely adore hearing from you and seeing your culinary creations. What did you love most about it? Did you make any amazing variations or discover a new favorite ingredient to add? Did your family rave about it? Leave a comment below, or better yet, share your photos on social media and tag me! Your feedback and shared experiences are what truly bring this community to life, inspiring us all to try new things and find joy in cooking. Happy cooking, my friends, and I can’t wait to hear all about your delicious Cheesy Cajun Garlic Chicken Rotini Skillet adventures!